Some Less Known Central Nervous System Depressant

CNS Depressant Effect of the Crude Extract of the Flowering Top of Rosa damascena (Rosaceae)

The ethanol extract of the flowering top of Rosa damascena (Rosaceae) was assessed for neuropharmacological activities in mice using a number of experimental models. It significantly prolonged the pentobarbitone-induced sleeping time in mice, and showed mild to moderate central nervous system depressant activity when assessed by the hole cross and the open field tests in mice model when given...

Short Communication Preliminary study on the central nervous system depressant effect of Picrorhiza kurrooa Royle. (Scrophulariaceae) in mice models

Picrorhiza kurrooa Royle. is a well known medicinal plant among the indigenous medical practitioners of India. Present study is the first time to report the activity on the central nervous system. Preliminary study of the hot water extract showed significant depressant activity on the hole board test as evidenced from the ambulation and head dipping scores. The extract showed better activity co...

Central nervous system depressant effects of the ethanolic extract of Cymbidium aloifolium (L.)

The ethanolic leaf extract of Cymbidium aloifolium (L.) was intended to evaluate the effect on the central nervous system (CNS) using a number of neuropharmacological experimental models in mice. The extract, at the dose of 200 and 400 mg/kg body weight, were shown to have CNS depressant activity by the reduction of locomotor and exploratory activities in the open field and hole cross tests. Th...

Anatomical and Histological Studies of Central Nervous System of Some Scorpions of Iran

Pharmacological evaluation of Pachyrrhizus erosus (L) seeds for central nervous system depressant activity.

The research work deals with the screening of ethanol and chloroform extracts of Pachyrrhizus erosus seeds for central nervous system (CNS) depressant activity. The Pachyrrhizus erosus seed is known to contain rotinoids, flavonoids and phenylfuranocoumarin derivatives as chemical components and is reported to have antifungal, antisecretory, insecticides, antibacterial and spasmolytic activity. ...